Kognitivne sposobnosti oboljelih od kronične opstruktivne bolesti pluća

master's thesis

• Title (english): Cognitive performance of Chronic Obstructive Pulmonary Disease patients: A comparison study
• Author: Lea Jakob
• Mentor: Jasminka Despot Lučanin (mentor)
• Committee member: Ljiljana Pačić Turk (predsjednik povjerenstva)
• Committee member: Sanja Darmopil (član povjerenstva)
• Committee member: Jasminka Despot Lučanin (član povjerenstva)
• Granter: University of Zagreb; Faculty of Croatian Studies; (Department of Psychology); Zagreb
• Defense date and country: 2017-07-05, Croatia
• Scientific / art field, discipline and subdiscipline: SOCIAL SCIENCES; Psychology

Abstract

Kronična opstruktivna bolest pluća (KOPB) jedan je od vodećih uzroka smrtnosti u svijetu te se predviđa da će do 2050. biti drugi vodeći uzrok smrtnosti. Pojedinci s dijagnozom KOPB-a imaju reduciranu fizičku pokretljivost, zadovoljstvo zdravljem i životom. Oštećenja kognitivnih funkcija povezuju se sa smanjenom oksigenacijom, jednom od glavnih posljedica dugoročne opstrukcije pluća. Oštećenja takve vrste doprinose lošoj dosljednosti uzimanja farmakoterapije i dovode do veće stope smrtnosti. Glavni cilj ovog istraživanja je utvrditi da li pojedinci s dijagnozom KOPB-a, čije svakodnevno funkcioniranje nije teško oštećeno, imaju oštećenja neurokognitivnih funkcija u usporedbi s uzorkom sudionika bez dijagnoze. Istraživanje je obuhvatilo 40 sudionika s KOPB-om i 45 sudionika kontrolne grupe (balansiranih s obzirom na dob, spol i obrazovanje), čije su kognitivne funkcije ispitane pomoću Hrvatske verzije Normacog kratke baterije, kratkog neuropsihologijskog skupa testova kojim se dobiva cjelovit pregled funkcija pojedinca u osam kognitivnih domena. Kako nisu pronađene razlike u rezultatima na mjerama kognitivnog funkcioniranja, možemo pretpostaviti da blaga opstrukcija pluća ne narušava kognitivno funkcioniranje. Kod sudionika s dijagnozom KOPB-a rezultati na određenim domenama kognitivnog funkcioniranja značajno su povezani s objektivnim mjerama plućnih funkcija, dok je razinu stresa, anksioznosti i depresivnosti moguće prognozirati putem subjektivnog doživljaja ograničenja svakodnevnog funkcioniranja uzrokovanih plućnim poteškoćama. Buduća istraživanja trebala bi podrobnije istražiti na koji način određene kognitivne funkcije deterioriraju s obzirom na trajanje bolesti i objektivne plućne poteškoće osoba s težim stupnjem oštećenja.

Abstract (english)

Chronic obstructive pulmonary disease (COPD) is one of the leading causes of mortality in the world and is propagating to become the second main cause of death by 2050. Individuals diagnosed with COPD have a reduced physical mobility, satisfaction with health and life as a whole. Impairments in cognitive functioning have been linked to lowered oxygenation, one of the main consequences of long-term COPD. Such impairments contribute to poor medication adherence and lead to higher mortality. The purpose of this study was to examine whether individuals with a diagnosis of COPD, whose everyday functioning was not severely affected by the illness, had impaired neurocognitive functions when compared to a matched sample without a diagnosis of COPD. Study included 40 patients and 45 control subjects (matched for age, gender and education), which were tested with the Croatian version of the Normacog Brief Battery, a short neuropsychological tool, which provides a comprehensive overview of eight cognitive domains. No differences were found on any of the measures and thus we could conclude that mild pulmonary impairment does not have a detrimental impact on cognitive functioning. Overall, the cognitive functioning in certain domain was significantly correlated to objective measures of lung function measures. The subjective experience of stress, anxiety, and depression was related to a subjective measure of everyday impairments related to lung problems, but not to objective lung functions. Further studies should explore how particular cognitive functions decline in relation to disease duration and pulmonary function decline in a more severely impaired sample.

• Keywords: kratka neurokognitivna procjena; kronična opstruktivna plućna bolest; kognitivne sposobnosti
• Keywords (english): Brief neurocognitive assessment; chronic obstructive pulmonary disease; cognitive functioning
• Language: croatian
• URN:NBN: urn:nbn:hr:111:191819
• Study programme: Title: Department of Psychology; Study programme type: university; Study level: graduate; Academic / professional title: magistar/magistra psihologije (magistar/magistra psihologije)
• Type of resource: Text
• File origin: Born digital
• Access conditions: Open access
• Created on: 2017-10-12 14:02:15